Dendritic cell therapy for breast cancer (mammary carcinoma) – treatment options & modern immunotherapies

Breast cancer is the most common tumor disease in women. Thanks to modern diagnostics, personalized therapies, and increasingly immunological approaches, more treatment options are available today than ever before.

The choice of therapy always depends on the type of tumor, stage, genetics, and general condition of the patient.

Dendritic cell therapy for breast cancer (mammary carcinoma) – treatment options & modern

Flotte

Traditional forms of treatment

1. Surgery (breast-conserving or mastectomy)

In early stages, surgery is often the first step. The goal is to remove the tumor completely.

2. Radiation therapy

Often used after breast-conserving surgery. It reduces the risk of local recurrence.

Note: Not all patients require radiation therapy—certain molecular tumor profiles now allow for tailored strategies.

3. Chemotherapy

Has a systemic effect throughout the body. Often used for aggressive or hormone receptor-negative tumors.

4. Anti-hormone therapy (endocrine therapy)

Effective for hormone receptor-positive tumors (ER/PR-positive).
These include:
Tamoxifen
Aromatase inhibitors
Ovarian suppression
CDK4/6 inhibitors (e.g., abemaciclib)

5. Antibody and targeted therapies

Modern antibodies and antibody-drug conjugates are used for HER2-positive tumors. Personalized drug options are available for genetic mutations such as ESR1, PIK3CA, and BRCA.

Modern immunotherapies for breast cancer

Immunotherapies aim to strengthen the immune system and specifically recognize and fight cancer cells. Immunological approaches include:

Medical inquiry

Dendritic cell therapy (DZT)

Dendritic cell therapy utilizes the patient's own immune system.

The process involves:

Blood cells are extracted
Cultivated into dendritic cells in a GMP laboratory
Loaded with tumor antigens
Matured into highly active immune cells
Reinjected into the skin

The goal is to activate T cells that can specifically recognize and attack tumor cells.

DCT is customized for each patient and can be used for various types of breast cancer, regardless of whether the tumor is hormone-positive, HER2-negative, or triple-negative.

Combination therapies – why they can be useful

In modern oncology, combinations are increasingly being used to exploit several biological mechanisms simultaneously.

Possible combinations to support the immune system:

DZT + immune system support

e.g.

glutathione
artesunate
resveratrol
selenium

These substances can help reduce oxidative stress and stabilize immune function.

DZT + endocrine therapy

For ER-positive breast cancer (e.g., luminal A/B).

DZT can complement the tumor-directed immune response in this case.

DZT + targeted therapies

In the case of mutations such as PIK3CA or ESR1, classic therapies can be combined with immunological strategies.

DZT + local procedures

e.g., cryoablation or ozone therapy as part of complementary approaches.

Angelziele

The goal of immunotherapy for breast cancer

Cancer Breast dendritic cell therapy IMMUMEDIC LLC

Activate the immune system
Make tumor cells more detectable
Reduce the tumor burden
Stabilize quality of life
Slow down the progression of the disease
Important: Each patient responds individually; immunotherapies are not a substitute for guideline-based treatment.

Crew

Dendritic cell therapy is a patient-specific immunological approach.

No promises of a cure are made.